Isolation and characterization of antibacterial and antioxidant compounds present in Combretum collinum subspecie suluense

Abstract

Isolation and characterization of antibacterial and antioxidant compounds present in Combretum collinum Sub specie Suluense Leaf extracts of six different plants, many of which are used by traditional healers, were screened for antibacterial activity. Ethyl acetate and Methanol extracts of Adina microcephaha, Combretum aurea, Combretum bracteosam, Combretum collinum, Filicium decipiens and Ficus moraceae were screened. Of these acetone extracted the highest mass of 118 mg from Filicium decipiens as compared to the extracts from the Adina microcephala, Combretum aurea, Combretum bracteosum, Combretum collinum and Ficus decipiens. Two unknown compounds were isolated, characterized and their minimum inhibitory concentrations were determined; compound A = 0.5689 mg/ml and compound E = 1.479 mg/ml. The chemical structure proposed for unknown compound A from Combretum collinum subsp suluense was determined by correlation of HNMR, FT-IR and GC-MS data. The chemical structure of compound E was not proposed because it was masked by a phthalate pollutant, the structure of which was confirmed by correlation of GC-MS, FT-IR and 1HNMR data. O O O O Proposed structure of compound from vial A Proposed structure of phthalate pollutant