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Browsing by Author "Mbazima, V. G."

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Delineating the mode of action used by lithium in modulating oxidate stress and inflamation in activated macrophage cells

Makola, Raymond Tshepiso (2015)

Lithium is an FDA-approved psychiatric drug that has been used for more than half a century as a preferred, gold standard treatment for bipolar disorders (Cade, 1949; Freland and Beaulieu, 2012). Numerous studies reported ...
Determination of the molecular mechanism(s) involved in the pro-apoptotic activity of momordica balsamina acetone extract in lung A549 cancer cells

Mudalahothe, Maedza (2019)

Plant-derived products have been used for years in the treatment of various ailments with low or no side effects. Thus, screening of medicinal plants for potential anticancer activity, in vitro, could help identify ...
Evaluation of ricinus communis semi-purified extracts' potential as anti-metastatic agents using metastatic breast cancer (MCF-7) cancer cells

Mabasa, Rixile Forever (2017)

The malignancy of cancer cells is responsible for the high death rate in patients diagnosed with metastatic cancers. Medicinal plants represent a reservoir of bioactive compounds that can be useful in the management of ...
In vitro evaluation of anticancer effect on momordica balsamina linn. leaf extract in human MCF-7 cancer cells

Boshielo, Itumeleng Tania (2017)

Cancer is a broad group of various diseases characterised by unregulated cell proliferation which leads to the formation of tumours (Vickers, 2004). Some tumours remain confined to their site of origin while some gain the ...
Investigating egg weight and expression of growth differentiation factor 9 gene in preovulatory ovarian follicles of Potchefstroom Koekoek chicken genotype

Hlokoe, Victoria Rankotsane (2023)

Poultry eggs are an essential source of animal protein, and their consumption has expanded drastically in recent decades. The study aimed to determine the relationship between egg weight and egg quality traits, ovarian ...
Investigation of single nucleotide polymorphisms of insulin-like growth factor 1 (IGF-1) gene and their association with growth traits in Kalahari red goat

Mokoena, Kwena (2022)

Weighing scales are typically out of reach for small-scale farmers due to expensive cost and a lack of operational expertise. However, understanding body weight and its relationship to linear body measures are critical for ...
Investigation of the probable anti-cancer effects of the crude methanol extract of dicerocaryum senecioides, (Klotzch) J. Abels, leaves on cervical HeLa cancer cell

Malemela, Kholofelo Mmanoko (2018)

Dicerocaryum senecioides is a plant widely used as a nutritional source. It is used also for treatment of measles, wounds and to facilitate birth in domestic animal and humans in many parts of southern Africa (Mampuru et ...
Momordica balsamina crude acetone leaf extract impedes the human HT-29 colon cancer cell invasiveness, migration and adhesion by inhibiting ros-mediated TNF-a/NF-kB/MMP-2/-9 signalling pathway

Serala, Karabo (2020)

Metastatic cancer remains incurable and accounts for 90% of cancer-related deaths (He et al., 2019). Therefore, there’s an urgent need to find anti-metastatic drugs with novel therapeutic targets (Zhang et al., 2018). ...

Browsing by Author "Mbazima, V. G."

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